Our science

PTS (para-toluenesulfonamide) is a small molecule anticancer drug independently developed by Gongwin Biopharm. According to in vitro studies, PTS can penetrate the cancer membrane in a short period of time in contact with cancer cells and accumulate in the cytoplasm in a large amount, and the concentration of cancer cells is several times relative to that in normal cells. When PTS enters cancer cells, it will rupture the intracellular lysosome, release lysozyme and cause necrosis of cancer cells.

 

PTS also promotes the release of cytochrome c from mitochondria in cancer cells (Cytochrome C) inhibits ATP synthesis and induces cancer cells to develop apoptosis.

This anticancer target and mechanism are very different from other anti-cancer drugs.

Traditional chemotherapy drugs are mainly systemic cell poisoning. Patients often need to bear the side effects of drugs on normal cells, such as bone marrow suppression, hair loss, rash, vomiting, etc.

The characteristic of PTS is that it acts directly on the tumor tissue as a direct guide. Because the scope of efficacy is specific an accurate, there is no such side effect that the patient can’t bear.